Zero-Contrast PCI

Zero-Contrast PCI

Zero-contrast percutaneous coronary intervention (zero-PCI) is a technique that aims to minimize or eliminate the use of contrast dye during a PCI procedure

It’s a strategy for performing PCI (percutaneous coronary intervention, or angioplasty with stenting) with minimal or no use of contrast dye.

Who Needs ?

  • Patients with chronic kidney disease (CKD) or at high risk for contrast-induced acute kidney injury (CI-AKI)
  • Those with severe renal impairment, including patients on hemodialysis with residual renal function
  • Patients who previously experienced contrast-induced AKI
  • Can be used for complex cases, including left main coronary artery interventions and chronic total occlusions

Advantages

  • Significantly reduces or eliminates the risk of contrast-induced nephropathy/AKI
  • Allows coronary intervention in high-risk CKD patients while preserving renal function
  • Can achieve high procedural success rates (90-100% in studies) even for complex lesions
  • May reduce hospitalization rates and improve long-term outcomes
  • Enables treatment of coronary disease without worsening kidney function in severe CKD

Key features

  • Uses intravascular ultrasound (IVUS) for imaging and guidance
  • May employ optical coherence tomography (OCT)
  • Utilizes angiographic road mapping from prior angiograms
  • Relies on physiological measurements like fractional flow reserve (FFR)

What PATIENTS SAYS !!

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